High Protein Italian Beef Pasta Bake

Featured in: Everyday Flour-First Dinners

This hearty Italian-American bake combines extra-lean ground beef with whole wheat pasta, colorful vegetables, and a rich tomato sauce. Topped with melted mozzarella and Parmesan, it delivers 33g of protein per serving while keeping calories at 370. The dish comes together in 50 minutes, making it ideal for busy weeknights or meal prep sessions. Customizable with optional turkey pepperoni for extra pizza-inspired flavor, or swap in cottage cheese for even more protein. Works beautifully with chickpea or lentil pasta for a gluten-free version.

Updated on Wed, 21 Jan 2026 14:33:00 GMT
Golden, bubbly mozzarella and Parmesan cheese blankets the baked High Protein Italian Beef and Pasta Bake in a 9x13 dish. Pin It
Golden, bubbly mozzarella and Parmesan cheese blankets the baked High Protein Italian Beef and Pasta Bake in a 9x13 dish. | hazelflour.com

The smell of this baking brings me back to Tuesday nights when wrestling with meal prep felt like an Olympic sport. I stumbled onto this recipe during a fitness phase when I needed something that felt indulgent but actually fueled my goals. The way the cheese bubbles up golden and brown while the tomato sauce simmers underneath made my tiny apartment feel like a nonnas kitchen. Now its the dish that disappears fastest at potlucks, and nobody guesses its packing 33 grams of protein per serving.

My brother in law actually asked for the recipe after swearing he hated anything labeled healthy or high protein. That was the moment I knew this dish was special enough to convert skeptics. We stood around the kitchen island picking at the edges while the kids ran around, and he admitted it tasted better than the version he orders from his favorite Italian place.

Ingredients

  • Whole wheat penne or rotini (300 g / 10.5 oz): The nutty flavor of whole wheat holds up better to baking than regular pasta and adds 4 extra grams of fiber per serving without anyone noticing the difference
  • Extra lean ground beef (450 g / 1 lb): Going 93% or 95% lean means you get all the protein without dealing with pools of grease when you pull it out of the oven
  • Medium onion, diced: Red onion works beautifully here if you want a slightly sweeter undertone that plays nicely with the bell pepper
  • Garlic (2 cloves), minced: Fresh garlic makes a noticeable difference, but I wont judge you for using the pre minced stuff in a pinch
  • Red bell pepper, diced: The sweetness balances the acidity of the tomatoes and adds this gorgeous pop of color throughout the dish
  • Mushrooms (100 g / 3.5 oz), sliced: Button mushrooms work fine but cremini or baby bella give you a deeper, meatier flavor that almost mimics Italian sausage
  • Baby spinach (100 g / 3.5 oz): Wilting it into the sauce means even veggie haters wont pick it out because it practically disappears into the flavors
  • Canned crushed tomatoes (700 ml / 24 oz): San Marzano tomatoes are worth the few extra cents for their naturally sweet flavor profile
  • Tomato paste (2 tbsp): This little tube concentrates everything and gives you that slow simmered flavor in just 5 minutes
  • Dried oregano (1 tsp): If you have fresh oregano growing somewhere, triple the amount and stir it in during the last minute of simmering
  • Dried basil (1 tsp): Swap in fresh basil only as a garnish because it loses all its magic if you cook it too long
  • Chili flakes (½ tsp, optional): Start with half this amount if youre serving anyone who claims they cant handle spice
  • Salt and freshly ground black pepper: Taste your sauce before salting because some canned tomatoes come already salted
  • Part skim mozzarella cheese (150 g / 5 oz), shredded: Buying a block and shredding it yourself melts better than the pre shredded stuff which has anti caking agents
  • Grated Parmesan cheese (30 g / 1 oz): The real stuff with the rind on it makes a difference, but the grated tub works in a budget week
  • Turkey pepperoni slices (30 g / 1 oz, optional): These get slightly crisp in the oven and give you that pepperoni pizza vibe without the grease
  • Fresh basil, for garnish (optional): Layer whole leaves on top in the last 2 minutes of baking so they turn into these crispy little basil chips

Instructions

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Get your oven ready first:
Preheat to 200°C (400°F) and move your oven rack to the center position so the cheese browns evenly without burning on top
Cook the pasta smart:
Boil the whole wheat pasta for 2 minutes less than the package directions since itll finish cooking in the oven, then drain immediately
Brown the beef properly:
Cook the ground beef in a large nonstick skillet over medium heat, breaking it into small crumbles and letting it develop some browned bits for extra flavor
Build your vegetable base:
Toss in the onion, garlic, bell pepper, and mushrooms, cooking for 5 to 7 minutes until the vegetables soften and smell fragrant
Add the spinach trick:
Stir in the baby spinach and watch how quickly it wilts down into almost nothing, about 1 minute
Create the sauce:
Pour in the crushed tomatoes, tomato paste, oregano, basil, chili flakes, salt, and pepper, then let everything simmer together for 5 minutes
Combine everything:
Mix the cooked pasta directly into the skillet with the beef and vegetable sauce so every piece gets coated
Prep for baking:
Transfer the whole mixture to a lightly greased 23x33 cm (9x13 inch) baking dish, spreading it evenly
Add the cheesy layer:
Sprinkle the mozzarella and Parmesan across the top and arrange turkey pepperoni slices if you decided to use them
Bake until bubbly:
Bake for 20 minutes until you see the cheese turning golden brown in spots and the sauce bubbling up around the edges
The finishing touch:
Scatter fresh basil over the top right before serving if you want that restaurant style presentation
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Fresh basil garnish adorns the savory High Protein Italian Beef and Pasta Bake with whole wheat penne and vegetables. Pin It
Fresh basil garnish adorns the savory High Protein Italian Beef and Pasta Bake with whole wheat penne and vegetables. | hazelflour.com

This recipe became my go to when my friend started training for a marathon and needed meals that actually fueled her recovery without feeling like diet food. We made huge batches on Sundays, and she said having this in her fridge kept her from ordering takeout after long runs when she was too tired to cook.

Make It Your Own

Stirring in 200 g of low fat cottage cheese or ricotta before baking adds an incredible creamy layer that bumps the protein even higher while making the texture feel more like a stuffed shell bake. I discovered this trick by accident when I had leftover ricotta in the fridge and now my family requests it this way every time.

Gluten Free Swaps

Chickpea or lentil pasta actually works beautifully here and adds an extra 3 to 4 grams of protein per serving while making the whole dish gluten free. Just watch the baking time closely because alternative pastas can go from perfect to mushy faster than wheat pasta.

Serving Suggestions

A crisp green salad with a simple vinaigrette cuts through the richness and makes the meal feel complete without adding much prep time. I also like serving it with roasted broccoli or steamed green beans on busy weeknights.

  • Warm some crusty whole wheat bread on the side for soaking up the extra sauce
  • Keep red pepper flakes on the table so spice lovers can add more heat
  • Double the recipe and freeze one unbaked tray for a future emergency dinner
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Slices of turkey pepperoni top the hearty High Protein Italian Beef and Pasta Bake, served ready for family dinner. Pin It
Slices of turkey pepperoni top the hearty High Protein Italian Beef and Pasta Bake, served ready for family dinner. | hazelflour.com

Theres something deeply satisfying about serving a dish that feels indulgent while knowing its nourishing your body. This bake manages to be both the comfort food youre craving and the fuel you actually need.

Recipe FAQs

Can I make this ahead of time?

Absolutely. Assemble everything up to step 8, cover tightly, and refrigerate for up to 24 hours. Bake when ready, adding 5-10 minutes to the cooking time if baking cold from the refrigerator.

What pasta shapes work best?

Penne and rotini are excellent choices because their ridges and curves hold onto the thick meat sauce. Shells, fusilli, or ziti also work well. Avoid long strands like spaghetti as they don't capture the chunky vegetable-beef mixture effectively.

Can I freeze leftovers?

Yes, individual portions freeze beautifully for up to 3 months. Cool completely, wrap tightly in freezer-safe containers, and thaw overnight in the refrigerator before reheating at 180°C (350°F) until heated through.

How can I increase the protein content further?

Stir in 200g low-fat cottage cheese or ricotta before baking, use legume-based pasta, or add diced grilled chicken to the beef mixture. Each modification adds 5-10g of protein per serving while maintaining the comforting texture.

What vegetables can I substitute?

Try zucchini, eggplant, or diced carrots instead of bell pepper. Kale or Swiss chard work well in place of spinach. For a Mediterranean twist, add artichoke hearts, sun-dried tomatoes, or black olives to the sauce mixture.

Is this suitable for gluten-free diets?

Simply substitute chickpea pasta, lentil pasta, or certified gluten-free wheat pasta. These alternatives often boost protein content even higher while keeping the dish accessible for those avoiding gluten. Always verify all other ingredients are gluten-free certified.

High Protein Italian Beef Pasta Bake

Hearty pasta bake with lean beef, vegetables, and melted cheese on whole wheat pasta. Perfect for meal prep.

Prep Time
20 minutes
Time to Cook
30 minutes
Total Duration
50 minutes
Recipe Creator Gabriel Lawson


Skill Level Easy

Cuisine Type Italian-American

Makes 6 Portions

Diet Preferences None specified

Ingredient List

Pasta

01 10.5 oz whole wheat penne or rotini

Beef & Vegetables

01 1 lb extra-lean ground beef
02 1 medium onion, diced
03 2 cloves garlic, minced
04 1 red bell pepper, diced
05 3.5 oz mushrooms, sliced
06 3.5 oz baby spinach

Sauce

01 24 oz canned crushed tomatoes
02 2 tbsp tomato paste
03 1 tsp dried oregano
04 1 tsp dried basil
05 1/2 tsp chili flakes
06 Salt and freshly ground black pepper, to taste

Cheese & Toppings

01 5 oz part-skim mozzarella cheese, shredded
02 1 oz grated Parmesan cheese
03 1 oz turkey pepperoni slices
04 Fresh basil, for garnish

How-To Steps

Step 01

Preheat Oven: Preheat oven to 400°F.

Step 02

Cook Pasta: Cook pasta in a large pot of boiling salted water until al dente. Drain and set aside.

Step 03

Brown Ground Beef: In a large nonstick skillet over medium heat, cook the ground beef until browned, breaking it up as it cooks. Drain excess fat if needed.

Step 04

Sauté Vegetables: Add onion, garlic, bell pepper, and mushrooms to the skillet. Sauté for 5–7 minutes until softened.

Step 05

Add Spinach: Stir in spinach and cook until wilted, about 1 minute.

Step 06

Prepare Sauce: Add crushed tomatoes, tomato paste, oregano, basil, chili flakes, salt, and pepper. Simmer for 5 minutes, allowing flavors to meld.

Step 07

Combine Pasta and Sauce: Combine the cooked pasta with the beef and vegetable sauce mixture.

Step 08

Transfer to Baking Dish: Transfer the mixture to a lightly greased 9x13 inch baking dish.

Step 09

Add Cheese Toppings: Sprinkle mozzarella and Parmesan evenly over the top. Arrange turkey pepperoni slices if using.

Step 10

Bake: Bake for 20 minutes, until cheese is melted and bubbly.

Step 11

Garnish and Serve: Garnish with fresh basil before serving, if desired.

Tools Needed

  • Large pot
  • Large nonstick skillet
  • 9x13 inch baking dish
  • Mixing spoon
  • Cheese grater

Allergen Details

Always review ingredients for allergens. If unsure, ask a healthcare professional.
  • Contains wheat (pasta)
  • Contains milk (cheese, optional cottage/ricotta cheese)
  • May contain soy (check processed meat or cheese labels)

Nutrition Details (one portion)

Nutrition listed here is for guidance only. It's not a substitute for medical advice.
  • Calorie Count: 370
  • Total Fat: 11 g
  • Total Carbs: 37 g
  • Protein: 33 g