Spinach Artichoke Grilled Cheese

Featured in: Everyday Flour-First Dinners

This gourmet spinach and artichoke grilled cheese elevates the classic sandwich with a creamy, savory filling. Sautéed fresh spinach and tender artichoke hearts blend with mozzarella, cream cheese, and Parmesan, creating a rich interior contrast against crispy, buttered sourdough. Ready in 25 minutes, it's an easy vegetarian lunch or dinner that pairs beautifully with tomato soup.

Updated on Sun, 18 Jan 2026 09:02:00 GMT
Golden sourdough slices cradle a creamy spinach artichoke grilled cheese filling, melted and oozy. Pin It
Golden sourdough slices cradle a creamy spinach artichoke grilled cheese filling, melted and oozy. | hazelflour.com

My neighbor handed me a jar of marinated artichokes one Saturday morning, insisting I had to try them in something other than pasta. I stood in my kitchen that afternoon, staring at the jar and a bag of spinach about to wilt, when it hit me: grilled cheese. Not just any grilled cheese, but one stuffed with that creamy spinach artichoke dip everyone devours at parties. The first bite off the griddle was so good I nearly burned my tongue, and I didn't care one bit.

I made these sandwiches for my sister during one of her surprise visits, and she ate hers standing at the counter, declaring it better than any restaurant version she'd tried. We ended up making a second round that night, laughing as cheese stretched between the halves. It became our thing whenever she'd show up unannounced, and I started keeping artichoke hearts stocked just in case.

Ingredients

  • Shredded mozzarella cheese (1 cup, 120 g): This is your melt champion, creating those gorgeous cheese pulls and binding everything together without overpowering the other flavors.
  • Cream cheese (1/2 cup, 60 g, softened): Let it sit on the counter for 20 minutes so it blends smoothly, no lumps, just creamy richness that holds the filling together.
  • Grated Parmesan cheese (1/4 cup, 25 g): This adds a sharp, salty punch that keeps the filling from tasting flat or one note.
  • Unsalted butter (2 tablespoons, softened): Soft butter spreads easily on the bread without tearing it, and it toasts up golden and crisp.
  • Fresh spinach (1 cup, 30 g, chopped): Wilting it first prevents a soggy sandwich, and chopping it ensures every bite has a bit of green.
  • Artichoke hearts (1/2 cup, 80 g, canned or jarred, drained and chopped): Squeeze out extra liquid with your hands or a paper towel, or the filling will weep moisture into the bread.
  • Garlic clove (1 small, minced): Fresh garlic is worth it here, its sharpness mellows as it mixes and adds depth.
  • Sourdough bread (4 slices): A sturdy bread with a bit of tang stands up to the rich filling and crisps beautifully without burning.
  • Salt (1/4 teaspoon): Just enough to wake up the vegetables and balance the creaminess.
  • Black pepper (1/8 teaspoon, freshly ground): Freshly ground pepper has a warmth that pre ground just can't match.
  • Red pepper flakes (pinch, optional): A tiny bit of heat cuts through the richness and keeps things interesting.

Instructions

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Wilt the spinach:
Heat a medium skillet over medium heat, toss in the spinach with just a splash of water, and watch it collapse into itself in about a minute or two. Drain it well, pressing out moisture with the back of a spoon, or your sandwich will get soggy.
Make the filling:
In a bowl, combine the wilted spinach, chopped artichokes, cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if you like a little kick. Stir until everything is evenly mixed and the cream cheese is fully incorporated.
Assemble the sandwiches:
Spread the spinach artichoke mixture generously onto two slices of sourdough, making sure it reaches the edges. Top with the remaining slices to form two sandwiches.
Butter the bread:
Spread softened butter evenly over the outside of each slice, all the way to the corners. This ensures every inch gets golden and crisp.
Grill the sandwiches:
Heat a large nonstick skillet or griddle over medium heat, place the sandwiches in, and cook for 3 to 4 minutes per side, pressing gently with a spatula. You want deep golden brown bread and melted, gooey cheese inside.
Serve:
Remove from heat, let them rest for just a moment, then slice in half and serve while they're still steaming. The cheese will be at its stretchiest right now.
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A close-up view shows the crisp, buttery bread exterior of the spinach artichoke grilled cheese. Pin It
A close-up view shows the crisp, buttery bread exterior of the spinach artichoke grilled cheese. | hazelflour.com

The first time I packed one of these for lunch, a coworker smelled it heating in the microwave and asked for the recipe before I'd even taken a bite. It's one of those dishes that makes people lean in and pay attention, not because it's fancy, but because it delivers comfort with a little bit of flair. I've made it on rainy afternoons, after long days, and once for a friend going through a breakup, and it always feels like the right choice.

Choosing Your Bread

Sourdough is my go to because its tangy flavor plays so well with the creamy filling, and its sturdy structure holds up under the weight of all that cheese. That said, a good multigrain or whole wheat adds a nutty sweetness and a bit more texture, while a classic white bread will give you pure nostalgic comfort. Avoid anything too soft or thin, it'll fall apart under the pressure and heat.

Making It Ahead

You can mix the spinach artichoke filling a day in advance and keep it covered in the fridge, which actually lets the flavors meld and deepen. When you're ready to eat, just assemble and grill as usual. I wouldn't recommend assembling the whole sandwich ahead of time, though, because the filling will soak into the bread and you'll lose that crispy golden crust.

Serving Suggestions

This sandwich is perfect on its own, but it becomes a full meal when you pair it with a bowl of tomato soup for dunking or a simple green salad with a sharp vinaigrette to cut the richness. I've also served it with pickles on the side, and the acidity is a brilliant contrast. Sometimes I'll add a handful of fresh basil to the filling or sprinkle smoked paprika on top before grilling for a little extra something.

  • Add a few slices of ripe tomato inside the sandwich for juicy bursts of acidity.
  • Swap mozzarella for fontina or Gruyere if you want a deeper, more complex flavor.
  • Try dipping it in marinara sauce or pesto for a fun twist.
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Serve this vegetarian spinach artichoke grilled cheese sandwich alongside a steaming bowl of tomato soup. Pin It
Serve this vegetarian spinach artichoke grilled cheese sandwich alongside a steaming bowl of tomato soup. | hazelflour.com

This recipe has become one of those reliable favorites I turn to when I want something satisfying without a lot of fuss. I hope it brings you the same kind of easy comfort it's brought me, one crispy, cheesy bite at a time.

Recipe FAQs

Can I prepare the spinach-artichoke filling ahead of time?

Yes, you can make the filling up to 2 days in advance. Store it in an airtight container in the refrigerator. Assemble and cook the sandwiches fresh when ready to serve.

What bread alternatives work best?

While sourdough is ideal for its tang and structure, whole wheat, multigrain, or brioche all work well. Avoid thin white bread that may tear. Choose bread thick enough to hold the filling without breaking.

How do I prevent the cheese from leaking out?

Spread the filling evenly but not to the very edges of the bread. Leave about a 1/4-inch border around all sides. Press gently while cooking rather than aggressively squeezing the sandwich.

Can I add protein to make it heartier?

Absolutely. Consider adding crumbled bacon, roasted chicken, or sun-dried tomatoes to the filling. These additions complement the spinach and artichoke flavors while increasing protein content.

What's the best way to achieve golden, crispy bread?

Use medium heat and ensure the butter is spread evenly on the bread exterior. Don't rush the cooking process. Each side needs 3-4 minutes to develop a golden crust while the cheese melts inside.

Is this suitable for meal prep?

The filling can be prepped ahead, but sandwiches are best assembled and cooked fresh. Cooked sandwiches can be wrapped in foil and reheated briefly, though texture is best enjoyed immediately after cooking.

Spinach Artichoke Grilled Cheese

Creamy spinach and artichoke filling nestled between golden sourdough slices for the ultimate comfort sandwich.

Prep Time
15 minutes
Time to Cook
10 minutes
Total Duration
25 minutes
Recipe Creator Gabriel Lawson


Skill Level Easy

Cuisine Type American

Makes 2 Portions

Diet Preferences Suitable for Vegetarians

Ingredient List

Dairy

01 1 cup shredded mozzarella cheese
02 1/2 cup cream cheese, softened
03 1/4 cup grated Parmesan cheese
04 2 tablespoons unsalted butter, softened

Vegetables

01 1 cup fresh spinach, chopped
02 1/2 cup canned or jarred artichoke hearts, drained and chopped
03 1 small garlic clove, minced

Bread

01 4 slices sourdough bread

Seasonings

01 1/4 teaspoon salt
02 1/8 teaspoon freshly ground black pepper
03 Pinch of red pepper flakes, optional

How-To Steps

Step 01

Prepare the spinach filling: In a medium skillet over medium heat, add spinach and a splash of water. Sauté for 1 to 2 minutes until wilted. Drain excess moisture thoroughly.

Step 02

Combine cheese and vegetable mixture: In a bowl, combine sautéed spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if using. Mix until well blended.

Step 03

Assemble the sandwiches: Spread the spinach-artichoke mixture evenly onto two slices of sourdough bread. Top with the remaining two bread slices to form sandwiches.

Step 04

Butter the bread exterior: Spread butter on the outer surfaces of all bread slices.

Step 05

Toast the sandwiches: Heat a large nonstick skillet or griddle over medium heat. Place sandwiches in the skillet and cook for 3 to 4 minutes per side, pressing gently, until bread is golden brown and cheese is fully melted.

Step 06

Finish and serve: Remove from heat, slice each sandwich in half diagonally, and serve immediately while hot.

Tools Needed

  • Medium skillet
  • Mixing bowl
  • Spatula
  • Nonstick skillet or griddle
  • Knife

Allergen Details

Always review ingredients for allergens. If unsure, ask a healthcare professional.
  • Contains milk from cheese and butter
  • Contains wheat from sourdough bread
  • May contain traces of soy or nuts depending on bread and cheese brands

Nutrition Details (one portion)

Nutrition listed here is for guidance only. It's not a substitute for medical advice.
  • Calorie Count: 430
  • Total Fat: 24 g
  • Total Carbs: 39 g
  • Protein: 16 g